Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1994-07-26
1997-09-16
Minnifield, N. M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4242041, 4241841, 435236, 435237, 4352351, 435239, A61K 39215, A61K 3938, C12N 700, C12N 708
Patent
active
056677855
ABSTRACT:
This invention relates to a temperature-sensitive (ts) feline infectious peritonitis (FIP) virus, which is characterized by substantially reduced growth at 39.degree. C. as compared with its growth at 31.degree. C. Also included in this invention is the use of the ts-FIP virus for oral or intranasal administration to cats as a vaccine to induce immunity against FIP.
REFERENCES:
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patent: 4571386 (1986-02-01), Fishman et al.
Platkin et al. 1988. Vaccines pp. 568-575; New Technologies for Making Vaccines.
Pedersen et al. 1985. Viral Diseases of Small Animals: Thirty Fourth Annual Symposium 7:1001.
Lutz, et al., J. Small Anim. Pract. 27:108(1986).
Pedersen, et al., Viral Diseases of Small Animals: Thirt-Fourth Annual Symposium 7;1001(1985).
Pedersen, et al., Am. J. Vet Res. 44:229*1983).
Scott, et al., "Attenuation of Feline Infectious Peritonitis Virus." Sixty-Ninth Conference of Research Workers in Animal Disease, Nov. 14-15, 1988.
Gerber Jay Dean
Ingersoll Jerald Dee
Ginsburg Paul H.
Koller Alan L.
Minnifield N. M.
Pfizer Inc.
Richardson Peter C.
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