Vaccine comprising Brucella abortus which has O polysaccharide a

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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42419711, 4242521, 424823, 4352521, 435822, 530350, 530352, 530359, A61K 3910, C12N 121

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057189030

ABSTRACT:
The present invention is an improved vaccine against Brucella abortus which permits differentiation between vaccinated and field strain infected cattle. The vaccine can be administered in two different forms: (1) cell envelopes isolated from an O polysaccharide antigen deficient, stable transposon mutant of B. abortus or (2) an O polysaccharide antigen deficient, stable transposon mutant of B. abortus.

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