Vaccine against rabies and process for preparation thereof

Details Vaccine against rabies and process for preparation thereof Vaccine against rabies and process for preparation thereof

1995-06-07

1998-11-03

Degen, Nancy

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

424 932, 4351723, 4352351, A61K 39205, C12N 701, C12N 1547

Patent

active

058304770

ABSTRACT:
The present invention relates to a vaccinia virus, characterized in that it contains all or part of a DNA sequence (I) coding for an antigenic glycoprotein of rabies.

REFERENCES:
patent: 4393201 (1983-07-01), Curtis et al.
patent: 4722818 (1988-02-01), Paoletti et al.
M.P. Kieny et al., Nature 312:163-166 (Nov. 8, 1984)m "Expression of rabies virus glycoprotein from a recomb. vaccinia virus".
T.J. Wiktor et al., P.N.A.S. 81:7194-7198 (Nov. 1984), "Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene".
Nature 336:416 (Dec. 1, 1987), "New vaccine and initiative mean end of rabies in sight for Europe?".
Wistar News Release, May 3, 1988, "The Wistar Institute announces new recombinant rabies vaccine trials in Western Europe, plans for U.S. trial".
International Herald Tribune, Thursday, May 19, 1988, "Rabies Vaccine Ready for Testing".
News/Sun-Sentinel, Thursday, May 5, 1988, "U.S. Test Sought of Vaccine".
DHHS Research Resources Report, vol. X, No. 4, Apr. 1986, "Recombinant DNA Research and Wildlife Studies Focus on Reducing the Spread of Rabies".
Paoletti et al., P.N.A.S. 81:193-197 (1984).
Panicali et al., P.N.A.S. 80:5364-5368 (1983).
Smith et al., P.N.A.S. 80:7155-7159 (1983).
Dietzschold et al., J. Virol. 44:595-602 (1982).
Verma, Biochim. Biophys. Acta 473:1-38 (1977).
Keller et al. (1980), Annales de Virologie 31(1):85-94 (Abstract only).

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