Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Reexamination Certificate
2004-06-21
2008-03-18
Graser, Jennifer E. (Department: 1645)
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
C424S234100, C424S185100, C424S190100, C530S300000, C530S350000
Reexamination Certificate
active
07344724
ABSTRACT:
The present invention discloses the existence of two novel proteins UspA1 and UspA2, and their respective genes uspA1 and uspA2. Each protein encompasses a region that is conserved between the two proteins and comprises an epitope that is recognized by the MAb 17C7. One or more than one of these species may aggregate to form the very high molecular weight form (i.e. greater than 200 kDa) of the UspA antigen. Compositions and both diagnostic and therapeutic methods for the treatment and study ofM. catarrhalisare disclosed.
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Aebi Christoph
Cope Leslie D.
Fiske Michael J.
Fredenburg Ross A.
Hansen Eric J.
Board of Regents , The University of Texas System
Fulbright & Jaworski LLP
Graser Jennifer E.
Wyeth Holdings Corporation
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