Use of treprostinil to improve kidney functions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

Reexamination Certificate

active

11012722

ABSTRACT:
The present invention describes novel methods for using Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof, for improving kidney functions, such as urine output, and treating symptoms associated with kidney malfunction or failure. The invention also relates to kits for the improvement of kidney functions and the treatment of symptoms associated with kidney malfunction or failure, comprising an effective amount of Treprostinil or its derivative, or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 4306075 (1981-12-01), Aristoff
patent: 5153222 (1992-10-01), Tadepalli et al.
patent: 6054486 (2000-04-01), Crow et al.
patent: 6441245 (2002-08-01), Moriarty et al.
patent: 6521212 (2003-02-01), Cloutier et al.
patent: 6528688 (2003-03-01), Moriarty et al.
patent: 2005/0080140 (2005-04-01), Hatae et al.
patent: 2005/0085540 (2005-04-01), Phares et al.
patent: 2005/0165111 (2005-07-01), Wade et al.
patent: 2005/0282901 (2005-12-01), Phares et al.
Clapp, L. H., et al., “Differential Effects of Stable Prostacyclin Analogs on Smooth Muscle Proliferation and Cyclic AMP Generation in Human Pulmonary Artery”, Am. J. Respir. Cell Mol. Biol., vol. 26, pp. 194-201 (2002).
Medline Plus® Medical Encyclopedia: Diabetic nephropathy, pp. 1-4, www.nlm.nih.gov/medlineplus/ency/article/000494.htm, date unavailable.
Medline Plus® Medical Encyclopedia: Immune response, pp. 1-3, www.nlm.nih.gov/medlineplus/ency/article/000821.htm, date unavailable.
Medline Plus® Medical Encyclopedia: Mesangial proliferative glomerulonephritis, pp. 1-3, www.nlm.nih.gov/medlineplus/ency/article/000487.htm, date unavailable.
Patterson, J. H., et al., “Acute Hemodynamic Effects of the Prostacyclin Analog 15AU81 in Severe Congestive Heart Failure”, The Amer. J. Card., vol. 75, pp. 26A-33A (1995).
Raychaudhuri, B., et al., “The Prostacyclin Analogue Treprostinil Blocks NFχB Nuclear Translocation in Human Alveolar Macrophages”, J. Biol. Chem., vol. 277, No. 36, pp. 33344-33348 (2002).
Shionoya, S., “Diagnostic criteria of Buerger's disease”, Intl. J. Cardio. 66 (Suppl. 1), pp. S243-245 (1998).
Tyle, P., “Iontophoretic Devices for Drug Delivery”, Pharma. Res., vol. 3, No. 6, pp. 318-326 (1986).
van Dijk, C., et al., “Pathogenesis of Diabetic Nephropathy”, Rev. in Endocrine & Metabolic Disorders, vol. 5, No. 3, pp. 237-248 (2004).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of treprostinil to improve kidney functions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of treprostinil to improve kidney functions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of treprostinil to improve kidney functions will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3731583

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.