Use of Russell's viper venom-induced plasma factor Xa...

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

Reexamination Certificate

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Details

C435S006120, C435S069100, C435S013000, C436S069000, C436S093000, C436S094000, C436S127000, C436S129000

Reexamination Certificate

active

10125627

ABSTRACT:
The invention relates to a method of monitoring the effect of a direct of indirect Factor Xa inhibitors comprising the steps of collecting a plasma sample from a patient, adding a solution of Russell's viper venom to the plasma sample and measuring the clotting time or the residual FXa activity chromogenically.

REFERENCES:
patent: 4946755 (1990-08-01), Yin
patent: 4946775 (1990-08-01), Yin
patent: 5187155 (1993-02-01), Fair
patent: 5886191 (1999-03-01), Dominguez et al.
patent: 6103888 (2000-08-01), Larrick et al.
patent: WO 97/24118 (1997-07-01), None
patent: WO 9724118 (1997-07-01), None
Hara et al. Thrombosis Research 1995 vol. 80, p. 99-104.

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