Use of NK-1 receptors antagonists for treating schizophrenic dis

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514254, 514256, 514278, 514333, 514339, A61K 31535, A61K 3150, A61K 31505, A61K 3144

Patent

active

061002569

ABSTRACT:
The present invention provides a method for the treatment or prevention of schizophrenic disorders using an orally active, long acting, CNS-penetrant NK-1 receptor antagonist and pharmaceutical compositions comprising such a NK-1 receptor antagonist.

REFERENCES:
patent: 5124332 (1992-06-01), Wise et al.
patent: 5132303 (1992-07-01), Toth et al.
patent: 5132309 (1992-07-01), Toth et al.
patent: 5162339 (1992-11-01), Lowe, III
patent: 5496833 (1996-03-01), Baker et al.
patent: 5538982 (1996-07-01), Hagan et al.
patent: 5612337 (1997-03-01), Baker et al.
patent: 5691336 (1997-11-01), Dorn et al.
patent: 5719147 (1998-02-01), Dorn et al.
patent: 5728695 (1998-03-01), Harrison et al.
Aguiar, M., et al., Physiology & Behavior, 1996, 60 (4) 1183-1186.
Barden, N., et al., J. Neurochem., 1983, 41, 834-840.
Brodin, E., et al., Neuropharmacology, 1987, 26 (6) 581-590.
Brodin, E., et al., Neuropeptides, 1994, 26, 253-260.
Culman, J., et al., J. Physiol. Pharmacol., 1995, 73, 885-891.
Cutler, et al., J. Psychopharmacol, 1994, 8, A22, 87.
Elliott, P. J., Exp. Brain Res. UK, 1988, 73, 354-356.
F-D-C Reports--Prescription Pharmaceuticals and Biotechnology, Dec. 8, 1997, 59 (49), 10.
File, S. E., Pharm. Biochem. Behavior, 1997, 58, 3, 747-752.
Kramer, et al., Science, 1998, 281, 1640-1645.
Lowe, J., et al., Drug News Perspect, 1992, 5 (4), 223.
Malek-Ahmadi, Neuroscience and Behavioral Reviews, 1992, 16, 365-359.
Rimon, R., et al., Biological Psychiatry, 1984, 19 (4), 509-516.
Roccon, et al., Pharmacological Research, 1995, 31, 191.
Shaikh, M., et al., Brain Research, 1993, 625, 283-294.
Shirayama, Y., et al., Brain Research, 1996, 739, 70-78.
Siegel, R., et al., Neurochem. Int., 1984, 6 (6), 783-789.
Siegel, A., et al., Aggressive Behavior, 1995, 21, 49-62.
Teixeira, R., et al., European J. Pharm., 1996, 311, 7-14.
Vassout, et al., Neuropeptides, 1994, 26 (Suppl. 1), 38.
Wahlestedt, Science, 1998, 281, 1624-1625.
Wall Street Journal, Aug. 13, 1998, B1, Col. 2.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Use of NK-1 receptors antagonists for treating schizophrenic dis does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of NK-1 receptors antagonists for treating schizophrenic dis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of NK-1 receptors antagonists for treating schizophrenic dis will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1150326

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.