Use of liposomal glucocorticoids for treating inflammatory...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

Reexamination Certificate

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C514S169000

Reexamination Certificate

active

07744920

ABSTRACT:
The present invention provides the use of a glucocorticoid (GC) or of a GC derivative encapsulated in a liposome for the preparation of a pharmaceutical composition for the treatment of an inflammatory associated condition in a subject, provided that said condition is not associated with a neurodegenerative disease or disorder. A specific use concerns a liposomal formulation comprising methylprednisolone sodium hemisuccinate (MPS) for the treatment of rheumatoid arthritis.

REFERENCES:
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patent: 10255106 (2004-06-01), None
patent: WO 2004047792 (2004-06-01), None
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Love, et al. (1990) Annals of Rheumatic Diseases, 49: 611-14.
Metselaar, et al. (2004) Ann. Rheum. Dis., 63: 348-53.
Mishina, et al. (1996) Pharmaceutical Research, 13(1): 141-45.

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