Use of cyclohexenone derivatives for the manufacture of a...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ketone doai

Reexamination Certificate

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Reexamination Certificate

active

06906107

ABSTRACT:
A preventive and/or therapeutic agent for dysuria, which comprises as an effective ingredient a cyclohexenone long-chain alcoholic derivative represented by the following formula (1): [wherein, R1, R2and R3each independently represents a hydrogen atom or a methyl group and X represents a linear or branched C10-28alkylene or alkenylene group]. This compound alleviates dysuria due to hypofunction of the urinary bladder so that they are useful as a preventive and/or therapeutic agent for dysuria

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Medline Abstract No. 95313596 of Cardozo et al., Gynecological endocrinology: official journal of the International Society of Gynecological Endocrinology, (Mar. 1995), 9 (1), 75-84.
Medline Abstract No. 2001487409 of Bihl et al., Lancet, (Aug. 25, 2001) 358 (9282) 651-6.
Medline Abstract No. 2004288267 of Rozenberg et al., Internation journal of fertility and women's medicine, (Mar.-Apr. 2004), 49(2), 71-4.
Yamaguchi et al., Tohoku Journal of Experimental Medicine (1976), vol. 119, No. 3, pp 211-222 (Abstract Only).
Dupont Mary C et al: “The neuronal response to bladder outlet obstruction, a role for NGF.” Advances in Experimental Medicine and Biology, vol. 385, 1995, pp. 41-54, XPOO1O79919 Symposium; Philadelphia, Pennsylvania, USA; Mar. 18-19, 1994, bladder function. 1995 Plenum Publishing Corp.; Plenum Press 233 Spring Street, New York, New York 10013, USA; London, England, UK ISBN: 0-306-45193-X * abstract; p. 45, p. 6-8 from the bottom *.

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