Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1995-01-11
1998-03-10
Ulm, John
Drug, bio-affecting and body treating compositions
Lymphokine
514 2, 514 8, 514 12, 514885, 530351, 4242781, A61K 3819
Patent
active
057258503
ABSTRACT:
A colony stimulating factor, CSF-1, is a lymphokine useful in treating or preventing bacterial, viral or fungal infections, neoplasms, leukopenia, wounds, and in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein.
REFERENCES:
patent: 4230697 (1980-10-01), Nishida et al.
patent: 4275056 (1981-06-01), Takaku et al.
patent: 4342828 (1982-08-01), Takaku et al.
patent: 4482485 (1984-11-01), Funakoshi et al.
patent: 4518584 (1985-05-01), Mark et al.
patent: 4604377 (1986-08-01), Fernandes et al.
patent: 4690915 (1987-09-01), Rosenberg
patent: 4808611 (1989-02-01), Cosman
patent: 4847325 (1989-07-01), Shadle et al.
patent: 4868119 (1989-09-01), Clark et al.
patent: 4879227 (1989-11-01), Clark et al.
patent: 5098702 (1992-03-01), Zimmerman et al.
patent: 5104650 (1992-04-01), Ralph et al.
Kalter et al.,J. of Immunol. (1991) 146:298-306.
Kunder et al., Anti. Res. (1993) 21:233-245.
Lloret et al., Arch. of Med. Res. (1992) 23:139-141.
Ralph et al., J. of Immunol. (1982) 129:427-432.
Munn et al., Blood (1988) 72:127a.
Bajorin et al., Proc. of ASCO (1990) 9:183.
Blum et al., Proc. of ASCO (1993) 12:474.
Motoyoshi, Oncology (1994) 51:198-204.
Miller et al., Proc. of ASCO (1990) 31:242.
Falk et al., J. of Leukocyte Biol. (1988) 43:471-476.
Suzu et al., Cancer Res. (1989) 49:5913-17.
Curley et al., Lymphokine Res. (1990) 9:355-363.
Thomassen et al., J. of Biolog. Response Modif. (1990) 9:87-91.
Butler, Oncology & Biotech News (1990) 1.
Hume et al., Immunol. Cell Biol. (1989) 67:243-249.
Ralph et al., Hemat. Growth Factors in Trans. Med. (1990) pp. 43-63.
Khwaja et al., British J. of Haemat. (1991) 77:25-31.
Chong et al., In Vivo Effect of Cytokines I No. 6842.
Komiyama et al., Blood (1988) 71:41-45.
Masaoka et al., Bone Marrow Trans. (1988) 3:121-127.
Hume et al., J. of Cellular Biochem. (1988) 38:127-138.
Broxmeyer et al., J. of Immunol. (1988) 141:3405-09.
Metcalf et al., Immunol. Cell Biol. (1987) 65:35-43.
Suzu et al., Jpn. J. Cancer Res. (1990) 81:79-84.
Adachi, T. et al., Cancer Immunol. Immunother(1993) 37:1-6.
Bermudez et al., 31st Interscience of Conf. on Antimicrobial Agents and Chemotherapy, Sep. 29 -- Oct. 2, 1991 (Program Abstract No. 31 (0).
Brugger, W. et al., Acta Haematol (1991) 86:138-147.
Bukowski, R.M. et al., J. of Clin. Oncology (1994) 12:97-106.
Cole, D.J. et al., J. of Natl'l Cancer Institute (1994) 86:39-51.
Dale, D., Clinical Infectious Diseases (1994) Supp2:S180-S188.
Denis, M., Clin. Exp. Immunol. (1991) 84:200-206.
Denis, M., J. of Leukocyte Biology (1991) 50:296-302.
Douzono, M. et al., Exp. Hematology (1992) 20:245.
Doyle, A. et al., Infect. & Immun. (1992) 60:1465-72.
Hume, D. et al., Lymphokine Research (1989) 8:69-77.
Kayashima, S. et al., Infect. & Immun. (1991) 59:4677-80.
Kunze, G. et al., J. Basic Microbiol. (1985) 25(2):141-144.
Langermans, J. et al., Biotherapy (1994) 7:169-178.
Lu, L. et al., Exp. Hematol. (1991) 19:804-809.
Lu, L. et al., Int. J. Cancer (1991) 47:143-147.
Mitraki, A. et al., Bio/Technology (1989) 7:690-697.
Morstyn, G. et al., Cancer Research (1988) 48:5624-5637.
Murray, H., Clinical Infectious Diseases (1993) 17(Suppl2):S407-13.
Petros W. et al., Exper. Hematology (1994) 22:582-586.
Redman B.G. et al., J. of Immunotherapy (1992) 12:50-54.
Roilides E. et al., Clinical Infectious Diseases (1992) 15:508-524.
Roilides E. et al., Hematology/Oncology Clinics of North America (1993) 7:841-864.
Sanda M. et al., J. of Clinical Oncology (1992) 10:1643-49.
Shiratsuchi H. et al., J. of Immunol. (1991) 146:3165-3170.
Tsakona C.P., et al., Bone Marrow Transplantation (1993) 11:433-436.
Tsukada H. et al., Amer. J. of Hematology (1994) 45:325-329.
VandePol C.J. et al., Biotechnology Therapeutics (1991) 2:231-239.
Weiner L.M. et al., Cancer Research (1994) 54:4084-4090.
Bock, S. et al., Cancer Research (1991) 51:2649-54.
Kitano et al., British J. of Research (1993) 85:176-178.
Yanai N. et al., Jpn. J. Cancer of Res. (1990 81:355-362.
Tsakona et al., Clin. Lab. Haemat. (1992) 14:273-280.
Hibbs, 1974, Science, 184:468-471.
Fidler, et al., 1981, Lymphokines, 3:345-363.
Fidler, 1975, J. of the National Cancer Institute, 55, 1159-1163.
Kleinerman, et al., 1983, Cancer Research, 43:2010-2014.
Marino et al., 1982, J. of Immunology, 128:2816-2823.
Kleinerman et al., 1983, J. of Clin. Invest., 72:304-315.
Cameron et al.,1979, J. Clin. Invest., 63:977-984.
Bucana et al., 1983, AJP, 112:101-111.
Churchill et al., 1975, J. of Immunology, 115:781-786.
Kleinerman et al., 1983, Lymphokine Research, 2:7-12.
Key, et al., 1982, Adv. Exp. Med. Biol., 146:265-314.
DeMaeyer, E., 1988, Interferons and Other Regulatory Cytokines, Wiley & Sons, Inc., Chpt. 10, pp. 195-220.
Paul, W.E., 1984, Fundamental Immunology, pp. 102-103.
Roitt, I.M., 1988, Essential Immunology, Sixth Edition, Chpt. 13, pp. 232-233, 236.
Sone, S., et al., 1986, Cancer Immunol Immunother, 21:93-99.
Erickson, K.L., et al., 1982, Cellular Immunology, 72:195-201.
Kleinerman, E.S., et al., 1984, Cancer Research, 44:4470-4475.
Arden-Jones, M.P., et al., 1988, Cellular Immunology, 113:361-375.
DeMaeyer, E., et al., 1988, Interferons and Other Regulatory Cytokines, Chpt. 8, pp. 154-173.
Stewart, W.E., II, The Interferon System, pp. 200-206, 224-231, 292-293, 309-310.
Higuchi, M., et al., 1990, The Journal of Immunology, 144:1425-1431.
Kern, D.E., et al., 1989, The Journal of Immunology, 143:4308-4316.
Saito, T., et al., 1987, Cancer Research, 47:673-679.
Ho, M., 1987, Ann. Rev. Med., 38:51-59.
Fidler, I.J., et al., 1985, The Journal of Immunology, 135(6):4289-4296.
Rosenberg, 1984, Science, 223:1412.
Dexter, 1984, Nature 309:746-747.
Vadas et al., 1983, J. Immunol. 130:795-799.
Clark, 1987, Science 236:1229-1237.
Sachs, 1987, Science 238:1374-1379.
Das et al., 1981, Blood 58:630-641.
Gough et al., 1984, Nature 309:763-767.
Fung et al., 1984, Nature 307:233-237.
Yokota et al., 1984, Proc. Natl. Acad. Sci. USA 81:1070-1074.
Wong et al., 1985, Science 228:810-185.
Lee et al., 1985, Proc. Natl. Acad. Sci. USA 82:4360-4364.
Cantrell et al., 1985, Proc. Natl. Acad. Sci. USA 82:6250-6254.
Ralph et al., 1986, Immunobiol. 172:194-204.
Ralph et al., 1983, Cell. Immunol. 76:10-21.
Ralph et al., 1987, Cell. Immunol. 105:270-279.
Warren et al., 1986, J. Immunol. 137:2281-2285.
Lee et al., 1987, J. Immunol. 138:3019-3022.
Metcalf, 1970, J. Cell. Physiol. 76:89-100.
Moore et al., 1984, Science 223:178-181.
Stanley, 1981, The Lymphokines, Stewart, II et al., ed. Humana Press, Clifton, NJ, pp. 101-132.
Byrne et al., 1981, Cell. Biol. 91:848-853.
Fleit et al., 1981, J. Cell. Physiol. 108:347-352.
Wing et al., 1982, J. Clin. Invest. 69:270-276.
Nogawa et al., 1980, Cell. Immunol. 53:116-124.
Ladner et al., 1987, Embo. J. 6: (9) :2693-2698.
Stanley, 1985, Methods Enzymol. 116:564-587.
Csejtey et al., 1986, Biochem. Biophys. Res. Comm. 138:238-245.
Moore et al., 1983, J. Immunol. 131:2374-2378.
Prystowsky et al., 1984, Am. J. Pathol. 114:149-156.
Stanley et al., 1972, J. Lab. Clin. Med. 79:657-668.
Stanley et al., 1981, J. Immunol. Meth. 42:253-284.
Wang et al., 1983, J. Cell. Bochem. 21:263-275.
Hunkapiller et al., 1984, Science 226:304-311.
Payvar et al., 1979, J. Biol. Chem. 254:7636-7642.
Colotta et al., 1984, J. Immunol. 132:936-944.
Goodson and Hunt, 1982, J. Surg. Res. 33:394-401.
Eisenger et al., 1988, Proc. Natl. Acad. Sci. USA 85:1937-1941.
Fotev et al., 1987, J. Pathol. 151:209-219.
Ishizaka et al., 1986, Exp. Hematol. 14:1-8.
Motoyoshi et al., 1978, Blood 52:1012-1020.
Motoyoshi et al., 1983, Blood, 62(3):685-688.
Warren et al., 1985, J. Immunol. 134(2) :982-989.
Metcalf, 1986, Blood 67(2) :257-267.
Das et al., 1982, J. Biol. Chem. 257:13679-13681.
Becker et al., 1987, J. Immunol. 139:3703-3709.
Metcalf, 1987, Immunol. Cell. Biol. 65:35-43.
Broxmeyer et al., 1987, Blood Cells 13:31-48.
Bagby, 1987, Blood Cells 13:147-159.
Adachi et al., 1987, Horumon to Rinsho 35(5) :555-562.
Tauber and Tauber, 1987, Nucl. Med. Biol. 14:407-419.
Aukerman Sharon Lea
Chong Kong T.
Devlin James
Ma Sylvia Hsieh
Ralph Peter
Blackburn Robert P.
Chiron Corporation
Mertz Prema
Potter Jane E.R.
Ulm John
LandOfFree
Use of CSF-1 to treat tumor burden does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of CSF-1 to treat tumor burden, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of CSF-1 to treat tumor burden will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-137086