Use of a composition comprising vitamin K1 oxide or a...

Details Use of a composition comprising vitamin K1 oxide or a... Use of a composition comprising vitamin K1 oxide or a...

2011-05-10

2011-05-10

Sullivan, Daniel M (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ketone doai

C568S326000

Reexamination Certificate

active

07939568

ABSTRACT:
The present invention is related to the use of a composition having an adequate pharmaceutical or cosmetic carrier or diluent and a sufficient amount of vitamin K1 oxide or its derivative for the treatment and/or the prevention of mammal dermatological lesions.The present invention is also related to a cosmetic composition having an adequate cosmetic carrier, phospholipids and vitamin K1 oxide or its derivative.

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Ryall, R.P., Nandi, D.L., Silverman, R.B., “Substituted Vitamin K Epoxide Analogues. New Competitive Inhibitors and Substrates of Vitamin K1 Epoxide Reductase”, J. Med. Chem 1990 (33) 1790-1797.
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Elson, MD, “Topical Phytonadione (Vitamin Ks) in the Treatment of Antinic and Traumatic Purpura”, Cosmetic Dermatology, vol. 8, No. 12, Dec. 1995, 6 pp. (which consist of 3 cover pages and pp. 25-27).
Lou, MD et al., “Effects of Topical Vitamin K and Retinol on Laser-Induced Purpura on Nonlesional Skin”, Dermatol Sug. vol. 25, No. 12, Dec. 1999, pp. 942-944.
Shah, MD et al., “The Effects of Topical Vitamin K on Bruising After Laser Treatment”, J Am Acad Dermatol, Aug. 2002, pp. 241-244.

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