Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-05-15
1991-12-31
Scalzo, Catherine S. Kilby
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514331, 514424, 514428, 546221, 546231, 548541, 548567, C07D21382
Patent
active
050773020
ABSTRACT:
Urea derivatives of the following formula: ##STR1## wherein R.sub.2 indicates a piperidino or pyrrolidino group which may be substituted with a hydroxy group or a lower alkyl group having 1 to 13 carbon atoms; A indicates an ethylene group, propylene group, butylene group or butenylene group; R.sub.2 indicates a straight or branched alkyl group having 1 to 20 carbon atoms, a benzyl group, or a phenyl group which may have 1 to 3 substituents such as a lower alkyl group having 1 to 6 carbon atoms, a lower alkoxy group having 1 to 3 carbon atoms, a halogen atom, a trifluoromethyl group, an amino group, a nitro group or a methylenedioxy group; and X indicates an oxygen or sulfur atom, as well as the hydrates and pharmaceutically acceptable salts thereof are useful antiulcer agents.
REFERENCES:
Chemical Abstracts Services, Abstract vol. 105:114968p (Kraemer), 1985.
Chemical Abstracts Services, Abstract vol. 95:42701, 1981.
Hamada Katsuhiro
Matsukubo Hiroshi
Matsumoto Toyomi
Miyashita Mitsutomo
Okamura Kyuya
Kilby Scalzo Catherine S.
Kyorin Pharmaceutical Co. Ltd.
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