Urea and thiourea derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C549S288000, C514S314000

Reexamination Certificate

active

07074933

ABSTRACT:
The invention is directed to a new class of quinolin-zene and z-exc chromen compounds that have been derivatized at the 6-position with a urea or this urea moet, and to then use as androgen antagonists.

REFERENCES:
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patent: 53073570 (1978-06-01), None
patent: 58102936 (1983-06-01), None
patent: 59164554 (1984-09-01), None
patent: WO 01/16108 (2001-03-01), None
patent: WO 01/16133 (2001-03-01), None
patent: WO 01/16139 (2001-03-01), None
El-Ansary, CA 124:331691, abstract of Egyptian Journal of Pharmaceutical Sciences, 1995, 36(1-6), pp 219-233.
Satpanthi, CA 55:33063, abstract of Current Science, 1960, vol. 29, pp 346.
Rep-pel, CA 65:3893, abstract of Pharmazie, 1966, vol 21(1), pp 30-36.
Mulwad, V.V. et al; “Synthesis of biologically active thiazolo-benzopyranyl-s-triazine derivatives”, 2003 Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry , 2003, 42B(3), pp. 621-626.
El-Ansary, S.L. et al;“Synthesis of trioxoperhydroimidazolyl benzopyrones with hypnotic activity”, Egyptian Journal of Pharmaceutical Sciences,1995, 36(1-6), pp. 219-233.
Merchant, J.R. et al; “Some reactions of aminocoumarins” Indian Journal of Chemistry Including Medicinal Chemistry, 1981, 20B(6), pp. 493-495.
Reppel, L. et al: “Coumarins. VI Preparation of coumarinylureas” Pharmazie, 1966, 21(1), pp. 30-36.
Satpanthi, P.S. et al: “Synthesis of coumarylthioureas” Current Science, 1960, 29, p. 346.
Kumar, Satyendra et al: “Thioureas from 6-amino-and 8-amino-7-hydroxy-4-methylcoumarins” J. Indinan Chem. Soc. 42(6), pp. 423-424, 1965.
English Abstract for JP59164554.
English Abstract for JP58102936.
English Abstract for JP53073570.

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