Unsaturated mTOR inhibitors

Details Unsaturated mTOR inhibitors Unsaturated mTOR inhibitors

2007-01-24

2010-02-09

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C544S350000, C546S199000, C549S059000

Reexamination Certificate

active

07659274

ABSTRACT:
Compounds represented by Formula (I)or a pharmaceutically acceptable salt thereof, are inhibitors of mTOR and useful in the treatment of cancer.

REFERENCES:
patent: 5869485 (1999-02-01), Missbach
patent: 6001839 (1999-12-01), Calderwood et al.
patent: 2002/0156081 (2002-10-01), Hirst et al.
patent: 2003/0073218 (2003-04-01), Shokat et al.
patent: 2003/0187001 (2003-10-01), Calderwood et al.
patent: 2005/0004142 (2005-01-01), Adams et al.
patent: 2005/0130994 (2005-06-01), Chen et al.
patent: 2006/0019957 (2006-01-01), Crew et al.
patent: 2006/0084654 (2006-04-01), Beck et al.
patent: 2006/0235031 (2006-10-01), Arnold et al.
patent: 2007/0112005 (2007-05-01), Chen et al.
patent: 2007/0149521 (2007-06-01), Crew et al.
patent: 2007/0167383 (2007-07-01), Roberts et al.
patent: 2007/0203143 (2007-08-01), Sheppard et al.
patent: 2007/0280928 (2007-12-01), Buck et al.
patent: 2007/0293516 (2007-12-01), Knight et al.
patent: 2008/0032960 (2008-02-01), Knight et al.
patent: 2009/0099174 (2009-04-01), Smith
patent: 2009/0124638 (2009-05-01), Shokat et al.
patent: 2007115620 (2007-10-01), None
patent: 2007126841 (2007-11-01), None
Bergstrom, D. et al. (1981) Journal of Organic Chemistry 46(7):1423-1431.
Bergstrom, D. et al. (1991) Journal of Organic Chemistry 56(19):5598-5602.
Bishop, A. et al. (1999) Journal of the American Chemical Society 121(4):627631.
Buzko, O. et al. (2002) Journal of Computer-Aided Design 16(2):113-127.
Hubbard, R.D. et al. (2007) Bioorganic & Medicinal Chemistry Letters 17(19):5406-5409.
International Preliminary Report on Patentability in PCT/US2006/044461.
International Search Report in PCT/US2006/044461.
International Search Report in PCT/US2007/002027.
Kinkade, C.W. et al. (2008) Journal of Clinical Investigation 118(9):3051-3064.
Legrier, M. et al. (2007) Cancer Research 67(23):11300-11308.
Papadimitrakopoulou, V. and Adjei, A.A. (2006) Journal of Thoracic Oncology 1(7): 749-751.
Prousek, J. (1984) Collection of Czechoslovak Chemical Communications 49(8):1788-1794.
Raslan, M.A. et al. (2000) Heteroatom Chemistry 11(2):94-201.
Seela, F. et al. (2000) Helvetica Chimica Acta 83(5):910-927.
Schram, K. et al. (1974) Journal of Carbohydrates, Nucleosides, Nucleotides 1(1):39-54.
Written Opinion of the International Search Authority in PCT/US2006/044461.
Written Opinion of the International Search Authority in PCT/US2007/002027.

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