Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-11-15
1992-12-08
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
53425, 2065241, A61K 3134
Patent
active
051698641
ABSTRACT:
A pharmaceutical composition is provided comprising an unbuffered iso-osmotic aqueous formulation containing an effective amount of ranitidine for the treatment of conditions mediated through histamine H.sub.2 receptors. The formulation has a pH of greater than or equal to 5.0 and less than 6.5 and preferably includes an osmotic adjusting agent chosen from the group consisting of dextrose and sodium chloride.
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Lachman et al The Theory and Practice of Idustrial Pharmacy (2nd Ed) (1976) pp. 586, 587, 588, 589, 590, 591, 598, 599, 600.
Galante et al, Stability of Ranitidine Hydrochloride at Dilute Concentration in Intravenous Infusion Fluids at Room Temperature, American Journal of Hospital Pharmacy, vol. 47, Jul. 1990, pp. 1580-1583.
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Johnson Douglas G.
Titus Allan E.
Baxter International Inc.
Flattery Paul C.
Rockwell Amy L. H.
Rose Shep K.
Schaafsma Paul E.
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