Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
1999-12-22
2008-11-04
Kaushal, Sumesh (Department: 1633)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S320100, C435S325000, C435S375000, C435S455000, C536S023100, C536S024200
Reexamination Certificate
active
07445890
ABSTRACT:
This invention relates to a DNA containing uncoupling protein-2 (UCP-2) promoter region containing the regulator sequence, a transformant transformed with the DNA, a method for screening a compound or its salt that promotes or inhibits UCP-2 promoter activity characterized by use of the transformant, a method for screening an antiobestic drug, an antidiabetic drug, a depressor, an antihyperlipemic drug, and an antipyretic drug characterized by use of the transformant, a kit for screening a compound or its salt that promotes or inhibits UCP-2 promoter activity characterized by use of the transformant, and pharmaceutical composition containing a compound or its salt that promotes or inhibits UCP-2 promoter activity obtained using the screening method or the screening kit.
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Igaki Shigeru
Kobayashi Makoto
Toyoda Yukio
Conlin David G.
Edwards Angell Palmer & & Dodge LLP
Kaushal Sumesh
Piffat Kathryn A.
Takeda Pharmaceutical Company Limited
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