Type of oligosaccharides and their sulfate derivatives

Details Type of oligosaccharides and their sulfate derivatives Type of oligosaccharides and their sulfate derivatives

2008-04-29

2008-04-29

Jiang, Shaojia Anna (Department: 1623)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S123100, C514S054000, C514S061000

Reexamination Certificate

active

10482977

ABSTRACT:
This invention involves a type of oligosacoharides and its their sulfate derivatives. The backbone of the oligosaccharides consists of 4 to 14 glucose residues, while the side chains contain 0 to 4 glucose residues. There are at least one 1->3α linkage and β-(1->3)-Iinkage or β-(1->4) linkage in the backbone. These oligosaccharides, and their sulfates have immune enhancing, antitumor, and antiviral activities. They can be used in immune enhancing, antitumor, and antiviral medicine compounds that would be used as therapeutic treatments.

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Moothoo, D. et al “Concanavalin A distorts the beta-GlcNAc . . . ” Glycobiology (1998) vol. 8, No. 2, 173-181.
Hirooka et al., “Dehydrative Glycosylation by Diethylaminosulfur Trifluoride (DAST)-Tin(II) Trifluoromethanesulfonate-Tetrabutylammonium Perchlorate-Triethylamine System” Bull. Chem. Soc. Japan, (1998) vol. 71, pp. 2893-2902.
Koto et al. “Dehydrative Glycosylation Using Heptabenzyl Derivatives of GLucobioses and Latose” Bull. CHem. Soc. Jpn. (1992) vol. 65, pp. 3257-3274.

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