Type I surface antigen associated with staphylococcus epidermidi

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

4241841, 4242791, 4242821, 4242341, A61K 39085, A61K 3900, A61K 4500, A61K 3902

Patent

active

058661409

ABSTRACT:
A process is disclosed for culturing clinical Staphylococcus epidermidis cells that reproducibly enables identification of a limited number of predominant serotypes. Two predominant serotypes common to most clinical cases of S. epidermidis have been identified and are denoted Type I and Type II. A particular polysaccharide surface antigen is associated with each of the Type I and Type II serotypes. The surface antigens can be used to provide active and passive immunization against S. epidermidis infection and to produce a hyperimmune immunoglobulin or antibodies for treatment of S. epidermidis infection.

REFERENCES:
patent: 4197290 (1980-04-01), Yoshida
patent: 4902616 (1990-02-01), Fournier et al.
patent: 5055455 (1991-10-01), Pier
patent: 5097020 (1992-03-01), Anderson
Kijima et al., "Antibody to the Capsular Polysaccharide/Adhesin Protects Rabbits against Catheter-Related Bacteremia . . . ", Jnl. of Inf. Dis., 162:435-441 (1990).
Yoshida et al., "Isolation of an Encapsulated Strain of Staphylococcus epidermidis", The Society for Applied Bacteriology, 47:299-301 (1979).
Tojo et al., "Isolation and Characterization of a Capsular Polysaccharide Adhesin from Staphylococcus epidermis", Jnl. of Infectious Diseases, 157:713-722 (1988).
Archer, "Staphylococcus epidermis: The organism, its diseases, and treatment", Corr. Clin. Topics Infect. Dis., pp. 25-48 (1984).
Ichiman et al., "The Relationship of Capsular-type of Staphylococcus epidermis to Virulence and Induction . . . ", Jnl. of Applied Bacteriology, 51:229-241 (1981).
Ichiman et al., Jnl. of Applied Bacteriology, 71:176-181 (1991).
Ichiman et al., "Protective antibodies in human sera against encapsulated strains of Staphylococcus epidermis", Jnl. of Applied Bacteriology, 63:165-169 (1987).
Robbins et al., "Prevention of Invasive Bacterial Diseases by Immunization with Polysaccharide Protein Conjugates", Current Topics in Microbiology and Immunology, 146:169-180 (1989).
Nelles et al., Infect. Imm., 49:14-18 (1985).
Fattom et al., Infect. & Immunity, 58:2367-2374 (1990).
McDonald et al., "Immunochemical Analysis of a Uronic Acid Polymer of Staphylococcus epidermis, Strain 53", Jnl. of Immunology, 105:389-395 (1970).
Aasen, et al., Antigenic Studies on Staphylococcus Epidermidis, Acta path. microbiol. Scand. Section B, 79:827-834 (1971).
Johnsen, et al., Studies on Polysaccharide C of Staphylococcus Epidermidis Acta path. microbiol. scand. Sect. B. 83:226-234 (1975).
Johnsen, et al., Studies on Polysaccharide C of Staphylococcus Epidermidis Acta path. microbiol. scand. Sect. B. 83:235-239 (1975).
Hussain, et al., Comparison of cell-wall teichoic acid with high-molecular-weight extracellular slime material from Staphylococcus epidermidis, J. Moc. Microbiol. vol. 5:368-375 (1992).
Endl, et al., Chemical composition and structure of cell wall teichoic acids of staphylococci, Arch Microbiol. 135:215-223 (1983).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Type I surface antigen associated with staphylococcus epidermidi does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Type I surface antigen associated with staphylococcus epidermidi, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Type I surface antigen associated with staphylococcus epidermidi will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1114692

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.