Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing oxygen-containing organic compound
Patent
1982-03-22
1984-08-28
Penland, R. B.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing oxygen-containing organic compound
435136, 435146, 435155, 435872, C12P 764
Patent
active
044684584
ABSTRACT:
A process for the preparation of a two-functional-group-containing terpenoid having the general formula: ##STR1## in which n is an integer of from 1 to 5, R represents a hydroxymethyl, formyl or carboxyl group, and A represents the hydrogen atom, or a 2-tetrahydropyranyl, benzyl, methoxymethol or methoxyethoxymethyl group comprising the oxidation with a microorganism belonging to the genus Nocardia. Some of the terpenoids are of value as anti-ulcer agents, while others are useful as intermediates.
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McOmie, "Protective Groups in Organic Chemistry", Plenum Press, (1973), pp. 6-107.
Sakagami et al., "Structure of Tremerogen A10", Agric. Biol. Chem., vol. 43, 2643-2645, (1979).
Taharo et al., "Antiulcer Polyprenyl Alcohols", Chemical Abstracts, Abstract Nos. 92:129133z and 92:129134a.
Tahara et al., "Antiulcer Decaprenylacetic Acid Derivatives", Chemical Abstracts, vol. 92, Abstract No. 111189n.
Abe Shinya
Kijima Shizumasa
Kuwana Noriaki
Nakajima Kenji
Sato Akio
Director General of the Agency of Industrial Science and Technol
Eisai Co. Ltd.
Penland R. B.
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