Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1996-09-17
1999-02-23
Scheiner, Toni R.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
4353201, 435 691, 536 235, 536 234, 536 231, C12N 1512, C12N 1585, C12N 121
Patent
active
058742867
ABSTRACT:
The present invention provides novel human tumor proteins (collectively called TUPRO) and polynucleotides which identify and encode TUPRO. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding TUPRO. The invention also provides pharmaceutical compositions containing TUPRO or antagonists to TUPRO, and in the use of these compositions for the treatment of diseases associated with the expression of TUPRO. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding TUPRO for the treatment of diseases associated with the expression of TUPRO. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, to hybridize to the genomic sequence or transcripts of polynucleotides encoding TUPRO or anti-TUPRO antibodies which specifically bind to TUPRO.
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DNA Search Results--SEQ ID No:Z.
Byrne, Genomics 35: 523, 1996--Aug. 31.
Au-Young Janice
Bandman Olga
Goli Surya K.
Hillman Jennifer L.
Billings Lucy J.
Incyte Pharmaceuticals Inc.
Johnson Nancy A.
Scheiner Toni R.
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