Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues
Reexamination Certificate
2006-12-12
2006-12-12
Helms, Larry R. (Department: 1643)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
C530S387100, C530S387300, C530S388100, C435S069100, C435S069700, C435S183000, C435S320100, C435S325000
Reexamination Certificate
active
07148326
ABSTRACT:
Tumor antigen inducing and/or activating HLA-A2-restricted tumor-specific cytotoxic T lymphocytes that is activated by recognizing HLA-A2 and a tumor antigen peptide, and a peptide or polypeptide derived from the tumor antigen, a polynucleotide encoding the peptide or a complementary strand polynucleotide thereof, a transformant comprising a recombinant vector which comprises the polynucleotide are provided.
REFERENCES:
patent: 5840839 (1998-11-01), Wang et al.
patent: 5874231 (1999-02-01), Sonenberg et al.
patent: 5936078 (1999-08-01), Kuga et al.
patent: 2000-189168 (2000-07-01), None
patent: WO97/21807 (1997-06-01), None
patent: WO 01/12660 (2001-02-01), None
Dermer, BioTechnology, 1994, 12:320.
Freshney, Culture of Animal Cells, A Manual of Basic Technique, Alan R. Liss, Inc., 1983, New York.
Riott et al (Immunology, Fourth Edition, 1996, Mosby, p. 7.9-7.11).
Bodey, et al (Anticancer Research 20: 2665-2676, 2000).
Cox, et al (Science 264: 716-719, 1994).
Ezzell (Journal of NIH Research 7: 46-49, 1995).
Spitler (Cancer Biotherapy 10: 1-3, 1995).
Boon (Advances in Cancer Research, 1992, 58: 177-210).
Arceci (Journal of Molecular Medicine 76: 80-93, 1998).
Lee, et al (Journal of Immunology 163: 6292-6300, 1999).
Zaks, et al (Cancer Research 58: 4902-4908, 1998).
Gao, et al (Journal of Immunotherapy 23: 643-653, 2000).
Hu, et al, Cancer Research 56: 2479-2483, 1996.
Jaeger, et al, International Journal of Cancer 66: 162-169, 1996.
Mukherji, et al, Proceedings of the National Academy of Science USA 92: 8078-8082.
Gura (Science 278: 1041-1042, 1997).
Rammensee et al,Immunogenetics, 41:178-228 (1995).
Meada et al,British Journal of Cancer, 87:796-804 (2002).
Masaaki Ito, et al. “Molecular Basis of T Cell-Mediated Recognition of Pancreatic Cancer Cells”Cancer Research 61, 2038-2046, Mar. 1, 2001.
Urur Shain, et al. “Human neoplasms elicit multiple specific immune responses in the autologous host” Pro. Natl., Acad. Sci. USA, vol. 92, pp. 11810-11813, Dec. 19995 Immuniology.
Damu Yang, et al. “Identification of a gene coding for a protein possessing shared tumor epitopes capable of inducing HLA-A24-restricted Cytotoxic T Lymphocytes in Cancer Patients” Cancer Research 59, 4056-4063, Aug. 15, 1999.
Megumi Kikuchi, et al., “Identification of Sart-1-derived peptide capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T Lymphocytes” Int. J. Cancer; 81, 459-466 (1999).
Shinya Gomi, et al. “A cyclophilin B gene encodes antigenic epitopes recognized by HLA-A24-restricted and tumor-specific CTLs1”, The Journal of Immunology pp. 4994-5004.
Shigeki Shichijo, et al. “A Gene Encoding Antigenic peptides of Human Squamous Cell Carcinoma Recognized by Cytotoxic T Lymphocytes” J. Exp. Med. vol. 187, No. 3, Feb. 2, 1998 277-288.
Tetsuya Nakatsura, et al. “Gene Cloning of Immunogenic antigens Overexpressed in Pancreatic Cancer” Biochemical and Biophysical Research Communication 281, 936-944 (2001).
Akira Yamada, et al. “Study of HLA class I restrication and the direction antigens of cytotoxic T lymphocytes at the tumor sites of ovarian cancer” Cancer Immunol. Immunother (1999) 48: 147-152.
Matthias Peiper, et al. “Pancreatic Cancer Associated Ascites-Derived CTL Recognize a Nine-Amino-Acid Peptide GP2 Derived from HER2
eu” Anticancer Research 19: 2471-2475 (1999).
Serafin Pinol-Roma, et al. “A novel heterogeneous nuclear RNP protein with a unique distribution on nascent transcripts” The Journal of Cell Biology, vol. 109 (No. 6, Pt. I) Dec. 1989 pp. 2575-2587.
Kanneganti G.K., et al. “The 160-kD subunit of human cleavage-polyadenylation specificity factor coordinates pre-mRNA 3′-end formation” Genes & Development 9: 2672-2683 1995.
Takahiro Nagase, et al. “Prediction of the Coding Sequences of Unidentified human genes. IV> The coding sequences of 40 new genes (KIAA0121-KIAA0160) Deduced by Analysis of cDNA Clones from Human Cell LIne KG-1)” DNA Research 2, 167-174, 1995.
International Search Report.
International Preliminary Examination Report.
Green Peptide Co., Ltd.
Helms Larry R.
Sughrue & Mion, PLLC
Tungaturthi Parithosh K.
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