Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.
Patent
1995-05-31
1998-02-03
Scheiner, Toni R.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
Tripeptides, e.g., tripeptide thyroliberin , etc.
530333, 530332, 530335, 530337, 564 34, 564 36, C07K 500, C07K 700, C07K 1700
Patent
active
057145806
ABSTRACT:
Novel compounds having activity against trypsin are disclosed. Specifically, novel peptide aldehyde analogues that have substantial potency and specificity as inhibitors of mammalian pancreatic trypsin are presented. The compounds are useful in the prevention and treatment of the tissue damage or destruction associated with pancreatitis.
Brunck Terence K.
Pearson Daniel A.
Pepe Michael G.
Webb Thomas R.
Corvas International Inc.
Huff Sheela J.
Scheiner Toni R.
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