Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2007-05-08
2007-05-08
Gupta, Anish (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C530S331000
Reexamination Certificate
active
10311519
ABSTRACT:
The prodrug of the invention is a modified form of a therapeutic agent and comprises a therapeutic agent, an oligopeptide of three amino acids, a stabilizing group and, optionally, a linker group. The prodrug is cleavable by a trouase enzyme such as Thimet oligopeptidase. Also disclosed are methods of making and using the prodrug compounds.
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Bebbington Christopher R.
Dubois Vincent
Gangwar Sanjeev
Lobl Thomas J.
Nieder Matthew H.
Gupta Anish
Lahive & Cockfield LLP
Medarex Inc.
Remillard, Esq. Jane E.
Soroos, Esq. Cynthia M.
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