Trimetazidine compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514253, 544376, 544398, 544399, 544401, A61K 31495, C07D295088, C07D295092, C07D40506

Patent

active

052832465

ABSTRACT:
The compounds are substituted trimetazidine useful for the treatment of ischaemic pathologies and peripheral vascular pathology.
A compound disclosed is 4-(2,3,4-trimethoxybenzyl)-1-[3-(4-hydroxy-2,3,5-trimethylphenoxy)propyl]p iperazine.

REFERENCES:
patent: 4100285 (1978-07-01), Murai et al.
patent: 4728650 (1988-03-01), Eziri et al.
Erizi et al., Chemical Abstracts, vol. 109, No. 22844 (1988) (Abstract for WO 87 05020, Aug. 27, 1987).

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