Tricyclic ketone derivatives as 5-HT antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514319, 514323, 514324, 514397, 540603, 546196, 546200, 546202, 548336, A61K 3155, C07D40908

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active

049391445

ABSTRACT:
The invention relates to ketones of the general formula (I): ##STR1## wherein Im represents an imidazolyl group of the formula: ##STR2## one of the groups represented by R.sup.1, R.sup.2 and R.sup.3 is a hydrogen atom or a C.sub.1-6 alkyl, C.sub.3-7 cycloalkyl, C.sub.3-6 alkenyl, phenyl or phenyl C.sub.1-3 alkyl group, and each of the other two groups, which may be the same or different, represents a hydrogen atom or a C.sub.1-6 alkyl group;

REFERENCES:
patent: 4808581 (1989-02-01), Oxford et al.
patent: 4814344 (1989-03-01), Humber et al.
patent: 4822881 (1989-04-01), Coates et al.
patent: 4859662 (1989-08-01), Coates et al.

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