Tricyclic heterocyclic sulfonamide and sulfonic ester derivative

Details Tricyclic heterocyclic sulfonamide and sulfonic ester derivative Tricyclic heterocyclic sulfonamide and sulfonic ester derivative

1997-06-11

1998-12-08

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514220, 5142245, 5142302, 514243, 514257, 540496, 540559, 540554, 540548, 540549, 544 9, 544252, 544183, 544184, A61K 3155, A61K 31505, C07D48700, C07D47100

Patent

active

058469699

ABSTRACT:
A sulfonamide derivative or a sulfonic ester derivative represented by the following general formula (I): ##STR1## {G represents an aromatic 5- or 6-membered ring; L represents O or --N(R.sup.1)-- (R.sup.1 represents hydrogen or lower alkyl); and M represents ##STR2## rings A and B represent each an unsaturated 5- or 6-membered ring; Y represents O, S(O).sub.n, C(R.sup.3)(R.sup.4), C(O), N(R.sup.5), CH(R.sup.6)CH(R.sup.7), C(R.sup.8).dbd.C(R.sup.9), N(R.sup.10)C(O), N.dbd.C(R.sup.11), OCH(R.sup.12), S(O).sub.n CH(R.sup.13) or N(R.sup.14)CH(R.sup.15).

REFERENCES:
R.M. Acheson, The Chemistry of Heterocyclic Compounds (1956), Ch.III, V.9:105-147.
G.P. Ellis, The Chemistry of Heterocyclic Compounds (1987), V.9.
G.P. Ellis, The Chemistry of Heterocyclic Compounds (1992), V.47, Part 2.
Capps et al., J. Med. Chem. (1992), V.35:4770-4778.
Boothroyd et al., J. Chem. Soc. (1953), Section 306, Part II, pp. 1504-1509.
Nodiff et al., J. Org. Chem. (1959), V.25:60-65.
Mital et al., J. Chem. Soc. (C) (1969), pp. 2148-2151.
Bendall et al., Aust. J. Chem. (1972), V.25:2451-2465.
Davy et al., Chemistry and Industry (1985), pp. 824-827.
Maller et al., J. of Labelled Compounds and Radiopharmaceuticals, V.XX, No. 12, pp. 1339-1349.

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