Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
2007-05-08
2010-06-08
Wilson, James O (Department: 1624)
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
Reexamination Certificate
active
07732604
ABSTRACT:
The invention relates to compounds of the formula Ior a pharmaceutically acceptable salt thereof, wherein R1, R2, R3and R4are as defined herein. The invention also relates to pharmaceutical compositions containing the compounds of formula I and to methods of treating hyperproliferative disorders in a mammal by administering the compounds of formula I.
REFERENCES:
patent: 6660744 (2003-12-01), Hirst et al.
patent: WO2005/004607 (2005-01-01), None
patent: WO 2005 004607 (2005-01-01), None
patent: WO 2005 028480 (2005-03-01), None
Dorwald F. A. Side Reactions in Organic Synthesis, 2005, Wiley: VCH, Weinheim p. IX of Preface.
Ma, P., et al., “c-METMutational Analysis in Small Cell Lung Cancer: Novel Juxtamembrane Domain Mutations Regulating Cytoskeletal Functions,”Cancer Research, 2003, 6272-6281, vol. 63.
Ma, P., et al., “c-MET: Structure, Functions and Potential for Therapeutic Inhibition,”Cancer and Metastasis Reviews, 2003, 309-325, vol. 22.
Maulik, G., et al., “Role of the Hepatocyte Growth Factor Receptor, c-MET, in Oncogenesis and Potential for Therapeutic Inhibition,”Cytokine&Growth Factor Reviews, 2002, 41-59, vol. 13.
Cheng Hengmiao
Cui Jingrong Jean
Hoffman Jacqui Elizabeth
Jia Lei
Johnson Mary Catherine
Liptak Vincent P.
Murray Jeffrey H
Pfizer Inc.
Wilson James O
Zielinski Bryan C.
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