Transferrin receptor genes and immunogenic compositions derived

Details Transferrin receptor genes and immunogenic compositions derived Transferrin receptor genes and immunogenic compositions derived

1995-06-07

1999-07-13

Degen, Nancy

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Amino acid sequence disclosed in whole or in part; or...

4241841, 4241851, 4242001, 4242341, 435 691, 530350, A61K 3900, A61K 3938, C07K 100

Patent

active

059223235

ABSTRACT:
Purified and isolated nucleic acid is provided which encodes a transferrin receptor protein of a strain of Haemophilus or a fragment or an analog of the transferrin receptor protein. The nucleic acid sequence may be used to produce peptides free of contaminants derived from bacteria normally containing the Tbp1 or Tbp2 proteins for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecule may be used in the diagnosis of infection. Also provided are recombinant Tbp1 or Tbp2 and methods for purification of the same. Live vectors expressing epitopes of transferrin receptor protein for vaccination are provided.

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