Transdiscal administration of cycline compounds

Details Transdiscal administration of cycline compounds Transdiscal administration of cycline compounds

2009-05-14

2011-11-29

Henley, III, Raymond (Department: 1629)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

3,10-dihydroxy-2-naphthacene carboxamide or derivative doai

C514S154000, C424S094650

Reexamination Certificate

active

08067397

ABSTRACT:
The present invention relates to administering a doxycycline compound into a diseased intervertebral disc.

REFERENCES:
patent: 3678158 (1972-07-01), Sussman
patent: 4341867 (1982-07-01), Johansen
patent: 4427649 (1984-01-01), Dingle et al.
patent: 4435506 (1984-03-01), Jackson et al.
patent: 4696816 (1987-09-01), Brown
patent: 5095037 (1992-03-01), Iwamitsu et al.
patent: 5116964 (1992-05-01), Capon et al.
patent: 5194596 (1993-03-01), Tischer et al.
patent: 5223248 (1993-06-01), McNamara et al.
patent: 5225538 (1993-07-01), Capon et al.
patent: 5231024 (1993-07-01), Moeller et al.
patent: 5258371 (1993-11-01), Golub et al.
patent: 5270300 (1993-12-01), Hunziker
patent: 5368841 (1994-11-01), Trauner et al.
patent: 5447851 (1995-09-01), Beutler et al.
patent: 5510370 (1996-04-01), Hock
patent: 5602156 (1997-02-01), Kohn et al.
patent: 5656272 (1997-08-01), Le et al.
patent: 5656644 (1997-08-01), Adams et al.
patent: 5728396 (1998-03-01), Peery et al.
patent: 5833984 (1998-11-01), Eibl et al.
patent: 5842477 (1998-12-01), Naughton et al.
patent: 5942499 (1999-08-01), Radomsky
patent: 5965583 (1999-10-01), Beers et al.
patent: 6049026 (2000-04-01), Muschler
patent: 6277969 (2001-08-01), Le et al.
patent: 6284471 (2001-09-01), Le et al.
patent: 6294170 (2001-09-01), Boone et al.
patent: 6300347 (2001-10-01), Revesz
patent: 6340369 (2002-01-01), Ferree
patent: 6352557 (2002-03-01), Ferree
patent: 6419944 (2002-07-01), Tobinick
patent: 6541477 (2003-04-01), Lewicki et al.
patent: 6554830 (2003-04-01), Chappius
patent: 6590081 (2003-07-01), Zhang
patent: 6593310 (2003-07-01), Cullis-Hill
patent: 6623472 (2003-09-01), Reincke et al.
patent: 6713246 (2004-03-01), Reinecke et al.
patent: 6756215 (2004-06-01), Wolfraim et al.
patent: 7067144 (2006-06-01), Demopulos et al.
patent: 7344716 (2008-03-01), DiMauro et al.
patent: 7429378 (2008-09-01), Serhan et al.
patent: 7553827 (2009-06-01), Attawia et al.
patent: 7799782 (2010-09-01), Munson et al.
patent: 2001/0006948 (2001-07-01), Kang et al.
patent: 2001/0016195 (2001-08-01), Tobinick
patent: 2001/0026801 (2001-10-01), Tobinick
patent: 2002/0010471 (2002-01-01), Wironen et al.
patent: 2002/0019351 (2002-02-01), Ke et al.
patent: 2002/0026244 (2002-02-01), Trieu
patent: 2002/0032155 (2002-03-01), Ferree
patent: 2002/0082697 (2002-06-01), Damien
patent: 2002/0107200 (2002-08-01), Chang et al.
patent: 2002/0169162 (2002-11-01), Smith et al.
patent: 2002/0198599 (2002-12-01), Haldimann
patent: 2003/0007972 (2003-01-01), Tobinick
patent: 2003/0039651 (2003-02-01), Olmarker
patent: 2003/0049256 (2003-03-01), Tobinick
patent: 2003/0069639 (2003-04-01), Sander et al.
patent: 2003/0134792 (2003-07-01), Pike et al.
patent: 2003/0207827 (2003-11-01), Boyle et al.
patent: 2003/0220692 (2003-11-01), Shapiro et al.
patent: 2004/0022864 (2004-02-01), Freyman et al.
patent: 2004/0126372 (2004-07-01), Banerjee et al.
patent: 2004/0193274 (2004-09-01), Trieu
patent: 2004/0228853 (2004-11-01), Serhan et al.
patent: 2004/0229786 (2004-11-01), Attawia et al.
patent: 2004/0229878 (2004-11-01), DiMauro et al.
patent: 2005/0025765 (2005-02-01), DiMauro et al.
patent: 2005/0038001 (2005-02-01), Attawia et al.
patent: 2005/0054595 (2005-03-01), Binette et al.
patent: 2005/0100538 (2005-05-01), Mohamed et al.
patent: 2005/0112091 (2005-05-01), DiMauro et al.
patent: 2005/0282783 (2005-12-01), Bujoli et al.
patent: 2006/0210552 (2006-09-01), Demopulos et al.
patent: 2007/0237777 (2007-10-01), DiMauro et al.
patent: 2007/0269413 (2007-11-01), Serhan et al.
patent: 2008/0213261 (2008-09-01), DiMauro et al.
patent: 2009/0068270 (2009-03-01), Attawia et al.
patent: 2009/0155364 (2009-06-01), Serhan et al.
patent: 2009/0162351 (2009-06-01), Brown et al.
patent: 2009/0162376 (2009-06-01), Brown et al.
patent: 2009/0175943 (2009-09-01), Attawia et al.
patent: 2003/263340 (2004-03-01), None
patent: 0 218 868 (1987-04-01), None
patent: 0 288 088 (1988-10-01), None
patent: 0 438 234 (1991-07-01), None
patent: 0 950 417 (1999-10-01), None
patent: 1 133 995 (2001-09-01), None
patent: 1 153 607 (2001-11-01), None
patent: 1 464 307 (2004-10-01), None
patent: WO 91/02078 (1991-02-01), None
patent: WO 92/07076 (1992-04-01), None
patent: WO 92/16553 (1992-10-01), None
patent: WO 93/16099 (1993-08-01), None
patent: WO 97/28828 (1997-08-01), None
patent: WO 98/24477 (1998-06-01), None
patent: WO 99/45923 (1999-09-01), None
patent: WO 2000/18409 (2000-04-01), None
patent: WO 2000/50079 (2000-08-01), None
patent: WO 01/85179 (2001-11-01), None
patent: WO 02/057240 (2002-07-01), None
patent: WO 02/100387 (2002-12-01), None
patent: WO 2003/000190 (2003-01-01), None
patent: WO 2004/022078 (2004-03-01), None
patent: WO 2005/000283 (2005-01-01), None
patent: WO 2005/011689 (2005-02-01), None
patent: WO 2005/049055 (2005-06-01), None
patent: WO 2005/053795 (2005-06-01), None
patent: WO 2005/110276 (2005-11-01), None
patent: WO 2006/031376 (2006-03-01), None
Abbas-Ghaleb, K., et al., “Preconcentration of Selenium Compounds on a Porous Graphitic Carbon Column in View of HPLC-ICP-AES Speciation Analysis,”Anal. Bioanal. Chem., 377: 1026-1031 (2003).
Ahn, N., et al., “Effect of Nutrient Concentration and OP-1 on the Metabolism of Intervertebral Disc: In Vitro Organ Culture Study,” 28,Abstracts of the 30th Annual Meeting of the International Society for the Study of the Lumbar Spine, Vancouver, Canada (May 2003).
Alini, M., et al., “A Biological Approach in Treating Disc Degeneration: Not for Today, but Maybe for Tomorrow,”Eur. Spine J.,11(Supp.2): S215-S220 (2002).
Allali, F., et al., “Increase in Bone Mineral Density of Patients with Spondyloarthropathy Treated with Anti-tumour Necrosis Factor α, ”Ann. Rheum. Dis., 62: 347-349 (2003).
Andonopoulos, A., et al., “Intra-articular Anti-tumor Necrosis Factor α Antibody in Recalcitrant Arthritis of Behcet's Disease,”Clinical and Experimental Rheumatology, 21(4 Suppl 30): S57-S58 (Jul.-Aug. 2003).
Aoki, Y., et al., “Local Application of Disc-related Cytokines on Spinal Nerve Roots,”Spine, 27(15): 1614-1617 (2002).
Arai, I., et al., “Pretreatment with Loxoprofen Sodium, 6-OHDA or Anti TNF-alpha Antibody Reduce Fos-like Immunoreactivity in Rat Experimental Lumber Disc Herniation,” 111,Abstracts of the 30th Annual Meeting of the International Society for the Study of the Lumbar Spine, Vancouver, Canada (May 2003).
Ariga, K., et al., “Mechanical Stress-induced Apoptosis of Endplate Chondrocytes in Organ-cultured Mouse Intervertebral Discs,”Spine, 28(14): 1528-1533 (2003).
Ashkenazi, A., et al., “Protection Against Endotoxic Shock by a Tumor Necrosis Factor Receptor Immunoadhesin,”Proc. Natl. Acad. Sci. USA, 88: 10535-10539 (1991).
Awasthi, Y., et al., “Purification and Properties of Human Erythrocyte Glutathione Peroxidase,”J.Biol. Chem., 250(13): 5144-5149 (1975).
Baker, D., et al., “Control of Established Experimental Allergic Encephalomyelitis by Inhibition of Tumor Necrosis Factor (TNF) Activity Within the Central Nervous System Using Monoclonal Antibodies and TNF Receptor-immunoglobulin Fusion Proteins,”Eur. J. Immunol., 24: 2040-2048 (1994).
Benjamin, L., et al., “A Plasticity Window for Blood Vessel Remodelling is Defined by Pericyte Coverage of the Preformed Endothelial Network and is Regulated by PDGF-B and VEGF,”Development, 125: 1591-1598 (1998).
Biemond, P., et al., “Protective Factors Against Oxygen Free Radicals and Hydrogen Peroxide in Rheumatoid Arthritis Synovial Fluid,”Arthritis Rheum., 27(7): 760-765 (1984).
Biskobing, D., “Novel Therapies for Osteoporosis,”Expert Opinion Invest. Drugs, 12(4): 611-621 (2003).
Boehm, J., et al., “New Inhibitors of p38 Kinase,”Exp. Opin, Ther. Patents, 10(1): 25-37 (2000).
Bokarewa, M., et al., “Local Infusion of Infliximab for the Treatment of Acute Joint Inflammation,”Ann. Rheum Dis., 62: 783-784 (2003).
Braun, J., et al., “Anti-tumour Necrosis Factor α Ther

Affiliated with

Also associated with

Rating

Transdiscal administration of cycline compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transdiscal administration of cycline compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transdiscal administration of cycline compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4301422