Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2007-05-01
2007-05-01
Vogel, Nancy (Department: 1636)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
55
Reexamination Certificate
active
10971982
ABSTRACT:
The present invention provides a substantially purified nucleic acid molecule encoding a p/CIP polypeptide, which regulates the activity of CBP/p300-dependent transcription factors. The invention also provides a substantially purified p-CIP polypeptide and active fragments thereof. In addition, the invention provides methods of identifying an effective agent that alters the association of a p/CIP polypeptide with a second protein. Further provided herein are methods of selectively inhibiting signal transduction pathways using an active fragment of a p/CIP polypeptide or a nucleic acid molecule encoding such an acive fragment.
REFERENCES:
GenBank Accession No. AF000581.
GenBank Accession No. AF000582.
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Glass Christopher K.
Rose David W.
Rosenfeld Michael G.
Torchia Joseph
Gordon & Rees LLP
The Regents of the University of California
Vogel Nancy
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