Tolerability of pharmaceutically active .beta.-amino acids

Details Tolerability of pharmaceutically active .beta.-amino acids Tolerability of pharmaceutically active .beta.-amino acids

1996-07-12

1999-08-10

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514561, 548535, 558432, 560 38, 560 48, 560122, 560125, 560153, 560168, 560170, 560171, 562443, 562457, 562504, 562507, 564164, 564189, A61K 3140

Patent

active

059359889

ABSTRACT:
The present invention relates to mixtures of .alpha.-amino acids and/or derivatives thereof and cyclopentane-.beta.-amino acids and/or derivatives thereof, dipeptides of the abovementioned .alpha.-amino acids and cyclopentane-.beta.-amino acids and mixtures of the abovementioned mixtures and dipeptides which have an improved tolerability in warm-blooded animals compared with the pure cyclopentane-.beta.-amino acids.

REFERENCES:
patent: 5037809 (1991-08-01), Miyauchi
patent: 5631291 (1997-05-01), Mittendorf
Derwent Abstract of JP 2-174-753, Agricultural Chemistry, p. 4, Derwent Week 9033 (1990).
H. Ohki, et al. J. Antibiot. vol. 44, No. 5, pp. 546-549 (1991).

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