Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-09-20
1997-02-25
Dentz, Bernard
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D47104
Patent
active
056060610
ABSTRACT:
The present invention provides a thioformamide derivative represented by the following general formula (I) or a pharmacologically acceptable salt thereof, which is highly safe, easy to use, and useful as an excellent hypotensive or heart disease remedy: ##STR1## wherein Y represents ##STR2## or the like [wherein R.sup.7 represents benzyloxy or the like; R.sup.11 and R.sup.12 each represent hydrogen, hydroxyl, benzoyloxy, benzyloxy, ##STR3## (wherein R.sup.14 and R.sup.15 each represent hydrogen, benzyl or the like) or the like];
REFERENCES:
patent: 4959385 (1996-09-01), Cool et al.
patent: 5064843 (1991-11-01), Hart et al.
patent: 5104883 (1992-04-01), Pilfreyman et al.
J. of Medicinal Chemistry, vol. 35, 1992, pp. 3613-3624 Brown et al. "Syntheses and biological activity of trans(.+-.)-N-Methyl-2-(3-pyridyl)-2-tetrahydrothiopyrancarbothioamide etc." p. 3613 and Table I.
Adachi Hideyuki
Hasegawa Takashi
Ishibashi Keiji
Kabasawa Yasuhiro
Katoh Hiroshi
Dentz Bernard
Eisai Co. Ltd.
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