Thiazolidine derivatives, their preparation and use

Details Thiazolidine derivatives, their preparation and use Thiazolidine derivatives, their preparation and use

1990-07-25

1992-04-14

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514337, 548183, 546269, C07D41712, A61K 31425

Patent

active

051048884

ABSTRACT:
Compounds of formula (I): ##STR1## (in which R.sup.1 -R.sup.7 are hydrogen or various organic groups, n is 1-10, Ar is an aromatic group, U is CH.sub.2 or a carbon atom doubly bonded to either one of its adjacent carbons, and W is >CH.sub.2, >C.dbd.O, >CHOH, >C.dbd.NOH or various derivatives thereof) have the ability to lower the levels of blood lipid peroxides and blood sugars and to inhibit the activity of aldose reductase; they may be used therapeutically for these purposes.

REFERENCES:
patent: 4572912 (1986-02-01), Yoshioka

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