Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1995-05-31
1997-03-25
Jordan, Kimberly
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514929, A61K 31425
Patent
active
056145420
ABSTRACT:
Thiazolidine derivatives of formula (I): ##STR1## (in which: R.sup.1, R.sup.2, R.sup.4, R.sup.5 are each hydrogen or alkyl; and R.sup.3 is hydrogen, aliphatic acyl, alkoxy-carbonyl, or arylcarbonyl and pharmaceutically acceptable salts thereof are anti-hypertensive agents and are useful in the treatment of obesity-related hypertension.
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Characterization of New Oral Antidiabetic Agent CS-045, Fujiwara et al, Diabetes, vol. 37, Nov. 1988, pp. 1549-1558.
Studies on Hindered Phenols and Analogues. 1. Hypolipidemic and Hypoglycemic Agents with Ability To Inhibit Lipid Peroxidation, Yoshioka et al, J. Med. Chem. 1989, 32, pp. 421-428.
CA 113(17):144852d, Faermark et al. (1990).
CA 108(5):31590u, Takada (1986).
Fujiwara Toshihiko
Horikoshi Hiroyoshi
Koike Hiroyuki
Nishino Hiroshi
Yoshioka Shinji
Jordan Kimberly
Sankyo Company Limited
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