Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2005-11-22
2005-11-22
Kifle, Bruck (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C540S544000
Reexamination Certificate
active
06967197
ABSTRACT:
A compound of formula (I) in which R1is halo, lower alkoxy, optionally substituted aryl, optionally substituted aryloxy, optionally substituted heterecyclic group or optionally substituted lower alkynyl, R2is amidated carboxy, R3is hydrogen or acyl, Ar is aryl or heterocyclic group, X is thia, sulfinyl or sulfonyl, Y and Z are each lower alkylene, m and n are each an integer of 0 to 2, and a salt thereof, useful as inhibitors of matrix metalloproteinases (MMP) or the production of tumor necrosis factor α (TNF α)
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patent: 97 24177 (1997-07-01), None
patent: 98 08823 (1998-03-01), None
patent: 98 08827 (1998-03-01), None
Imamura Yoshimasa
Mizutani Tsuyoshi
Mukai Noriko
Neya Masahiro
Ohne Kazuhiko
Fujisawa Pharmaceutical Co. Ltd.
Kifle Bruck
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