Tetrahydropyridazinone derivatives, processes for their preparat

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514218, 514222, 514226, 514230, 514228, 514229, 514231, 514232, 514234, 514235, 514247, 514252, 514253, 540460, 540492, 540524, 540525, 544 3, 544 54, 544 56, 544 582, 544 586, 544 61, 544 63, 544 66, 544 67, 544 68, 544 72, 544 82, 544 96, 544 98, 544114, 544182, 544215, 544220, 544222, 544223, 544238, 544239, C07D23702, C07D40104, C07D40304, A61K 3150

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046669027

ABSTRACT:
Tetrahydropyridazinones of the formula I ##STR1## wherein R denotes an optionally substituted carbocyclic or heterocyclic radical, R.sup.1 denotes hydrogen; alkyl; aralkyl, which is optionally substituted in the aryl part; or acyl, and R.sup.2 denotes hydrogen; alkyl, which can optionally be substituted; or optionally substituted phenyl; and their acid addition compounds, if these can be prepared.
The tetrahydropyridazinone derivatives of the formula I according to the invention and their physiologically acceptable salts exhibit useful pharmacological actions.

REFERENCES:
patent: 4055644 (1977-10-01), Houlihan
patent: 4404203 (1983-09-01), Sircar
patent: 4521416 (1985-06-01), Sircar
Wamhoff et al, Chem Abs. 71,61314t, (1969).

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