Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-01-23
2007-01-23
Davis, Zinna N. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S146000
Reexamination Certificate
active
10512925
ABSTRACT:
The present invention is directed to compounds of the formula I: I(wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2
REFERENCES:
patent: 5691321 (1997-11-01), Schaper et al.
Van Riper et al., “Characterization and Species Distribution of High Affinity GTP-couples Receptors for HumanRantes and Monocyte Chemoattractant Protein 1”, J. Exp. Med., vol. 177, pp. 851-856 (1993).
Butora Gabor
Goble Stephen D.
Guiadeen Deodialsingh
Jiao Richard
Kothandaraman Shankaran
Davis Zinna N.
Merck & Co. , Inc.
Merck Sharp & Dohme Limited
Rose David L.
Rubin David A.
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