Tetrahydro-benzthiazoles, the preparation thereof and their use

Details Tetrahydro-benzthiazoles, the preparation thereof and their use Tetrahydro-benzthiazoles, the preparation thereof and their use

1988-10-12

1989-12-12

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514367, 548161, 548163, 548164, 546198, 540603, 544135, C07D27782, A01K 31425

Patent

active

048868124

ABSTRACT:
This invention relates to new tetrahydrobenzthiazoles of general formula ##STR1## wherein R.sub.1 represents a hydrogen atom, an alkyl group, an alkenyl or alkynyl group, an alkanoyl group, a phenyl alkyl or phenyl alkanoyl group, while the above mentioned phenyl nucleic may each be substituted by 1 or 2 halogen atoms,
R.sub.2 represents a hydrogen atom or an alkyl group,
R.sub.3 represents a hydrogen atom, an alkyl group a cycloalkyl group, an alkenyl or alkynyl group, an alkanoyl group, a phenyl alkyl or phenyl alkanoyl group, while the phenyl nucleus may be substituted by fluorine, chlorine or bromine atoms,
R.sub.4 represents a hydrogen atom, an alkyl group, an alkyl or alkenyl group, or
R.sub.3 and R.sub.4 together with the nitrogen atom between them represent a pyrrolidino, piperidino, hexamethyleneimino or morpholino group, the enantiomers and the acid addition salts thereof.
The compounds of general formula I above in which one of the groups R.sub.1 or R.sub.3 or both groups R.sub.1 and R.sub.3 represent an acyl group are valuable intermediate products for preparing the other compounds of general formula I which have valuable pharmacological properties. The new compounds may be prepared using methods known per se.

REFERENCES:
patent: 4337343 (1982-06-01), Maillard et al.

Affiliated with

Also associated with

Rating

Tetrahydro-benzthiazoles, the preparation thereof and their use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tetrahydro-benzthiazoles, the preparation thereof and their use , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tetrahydro-benzthiazoles, the preparation thereof and their use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2121875