Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2005-09-27
2005-09-27
Wax, Robert A. (Department: 1653)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S252300, C435S254110, C435S320100, C435S325000, C536S023500
Reexamination Certificate
active
06949364
ABSTRACT:
A gene expressed specifically in the testis has been unexpectedly isolated in the course of studies of the expression of a gene encoding an unknown protein that triggers cell death. The isolated gene was a novel gene sequence that had no significant homologue in the database. This gene was also found to be involved in the regulation of differentiation in the testis.
REFERENCES:
Propst, F. et al., “Genetic Analysis and Developmental Regulation of Testis-Specific RNA Expression of Mos, Abl, Actin and Hox-1.4,” (1988), Oncogene, 2:227-33.
Sarge K. D. et al., “Expression of Heat Shock Factor 2 in Mouse Testis: Potential Role as A Regulator of Heat-Shock Protein Gene Expression During Spermatogenesis,” (1994), Biology of Reproduction, 50:1334-1343.
Toshima, J. et al., “Identification and Characterization of a Novel Protein Kinase, TESK1, Specifically Expressed in Testicular Germ Cells,” (1995), The Journal of Biological Chemistry, 270:31331-31337.
Kramer, W. et al., “Oligonucleotide-Directed Construction of Mutations Via Gapped Duplex DNA,” (1987) Methods in Enzymology, 154:350-367.
Presta A et al., Copper Binding to Rabbit Liver Metallothionein Formation of a Continuum of Copper(I)-Thiolate Stolchiometric Species, (1995), Eur. J. Biochem., 227:226-240.
Sambrook J. et al., “Hybridization of Radiolabelled Probes to Immobilized Nucleic Acids,” Molecular Cloning 2nd edition, 9.47-9.58, Cold Spring Harbor Lab. 1989.
Wilbur et al., “Rapid Similarity Searches of Nucleic Acid and Protein Data Banks,” Proc. Natl. Acad. Sci. (1983) 80:726-730.
Mizushima et al., “pEF-BOS, a Powerful Mammalian Expression Vector,” Nucleic Acids Research, 1990, 18(17), p. 5322-5323.
Cano-Gauci et al., “Reversible Zinc Exchange Between Metallothionein and the Extrogen Receptor Zinc Finger,” (1996) FEBS Letters, 386 (1):1-4.
Chabot B. et al., The Proto-Oncogene c-kit Encoding a Transmembrane Tyrosine-Kinase Receptor Maps to the Mouse W. Locus, (1988) Nature 335 (6185):88-9.
Yoshinaga K. et al., “Role of c-kit in Mouse spermatogenesis: Identification of Spermatogonia as a Specific site of c-kit Expression and Function,” (1991) Development 113 (2):689-99).
Unni E. et al., “Stage-Specific Distribution of the Spermatid-Specific Histone 2B in the Rat Testis,” (1995) Biology of Reproduction, 53(4):820-826.
Kaul Sunil C.
Mitsui Youji
Sugihara Takashi
Wadhwa Renu
Chugai Seiyaku Kabushiki Kaisha
Foley & Lardner LLP
National Institute of Advanced Industrial Science and Technology
Wax Robert A.
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