Chemistry: analytical and immunological testing – Optical result – With reagent in absorbent or bibulous substrate
Patent
1988-07-27
1992-12-08
Johnston, Jill A.
Chemistry: analytical and immunological testing
Optical result
With reagent in absorbent or bibulous substrate
422 56, 422 57, 422 58, 427 2, G01N 3122, G01N 3352
Patent
active
051697874
ABSTRACT:
The present invention provides a test carrier for the determination of an analyte from whole blood with the help of reagents contained in the test carrier, said test carrier having a blood application side to which blood is applied, an evaluation side on which, as a result of the reaction of the reagents with the analyte, an optically detectable change takes place, and an erythrocyte separation means between the blood application side and the evaluation side, wherein the erythrocyte separation means includes an integral composite having a first zone, which contains a polymeric film former, kieselguhr and a pigment, and thereupon, with formation of a transition region, a second zone containing a polymeric film-former, formed by liquid coating the first zone facing the blood application side and the second zone facing the evaluation side of the integral composite. The present invention also provides a process for the production of this test carrier and a method for analyzing blood samples using it.
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Knappe Wolfgang-Reinhold
Scheithauer Dieter
Boehringer Mannheim GmbH
Johnston Jill A.
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