Technetium-labelled diagnostic agent for the examination of the

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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128659, 424 15, 424 9, A61K 4900, A61K 4300, G01T 100

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active

042910129

ABSTRACT:
A process is disclosed for the preparation of a diagnositc agent for scanning the RES, in particular the liver, by mixing the sodium salt of 1-phenyl-2,3-dimethyl-pyrazolone-4-methylamino-methylsulfonic acid or 1-phenyl-2,3-dimethyl-pyrazolone in aqueous solution with tin(II) salt, adjusting the solution to a pH between 4 and 9, optionally lyophilizing the mixture and adding .sup.99m Tc-pertechnetate in physiological saline solution.

REFERENCES:
patent: 3743713 (1973-07-01), Kato et al.
patent: 4066742 (1978-01-01), Garrett
patent: 4087516 (1978-05-01), Laidler et al.

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