Technetium-99m labeled radiodiagnostic agents for liver and bone

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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2523011R, A61K 2900, A61K 4300

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active

040426769

ABSTRACT:
An improved technetium-99m labeled colloid and method of preparation comprising reducing technetium-99m with stannous oxalate and stabilizing with sodium phytate. This radiodiagnostic agent is useful in the scintigraphic examination of the recticuloendothelial system, particularly the liver. In addition, by autoclaving this product with saline, it becomes a superior bone marrow scanning agent.

REFERENCES:
patent: 3875299 (1975-04-01), Winchell et al.
Aburano et al., Life Sciences, vol. 12, June 30, 1975, Abstract No. 33622, p. 3371.
Columbetti, Radiobiol.-Radiother, Jan. 1974, pp. 47-51.
Johnson et al., Journ. of Nuclear Medicine, vol. 11, No. 1, (1970) pp. 564-565.
Sewakar et al., Nuclear Medicine, vol. XIV, No. 1, Mar. 31, 1975, pp. 46-51.
Subrumanian et al., J. of Nucl. Med., vol. 11, No. 6, 1970, pp. 365-366.

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