Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1994-07-20
1996-08-20
Marx, Irene
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435 41, 4352404, 43524046, 43524048, 549510, C12P 1702, C12P 100
Patent
active
055478662
ABSTRACT:
The present invention provides haploid cells and their derivatives which are cultured in vitro to produce taxanes and other metabolites that evolve from the isoprenoid biosynthesis pathway.
REFERENCES:
patent: 5019504 (1991-05-01), Christen
Zenkteler, M.A., et al. (1970) "Cytological studies on the regenerating mature female gametophyte of Taxus baccata L. and mature endosperm of Tilia platyphyllos Scop. in vitro culture", Acta Sacietatis Botanicorum Poloniae, 1:161-173.
Gibson, D. M., et al. (1993) "Initiation and growth of cell lines of Taxus brevifolia (Pacific yew)", Plant Cell Reports, 12:479-482.
Fett-Neto, Arthur G., et al. (1993) "Improved Growth and Taxol Yield in Developing Calli of Taxus cuspidata by Medium Composition Modification", Bio/Technology, 11:731-734.
Rohr, Rene (1982) "Activation et proliferation des cellules du megagametophyte de Taxus cultive in vitro", Can. J. Bot., 60:1583-1589.
Fett-Neto, Arthur G., et al. (1992) "Cell Culture of Taxus as a Source of the Antineoplastic Drug Taxol and Related Taxanes", Biotechnology, 10:1572-1575.
Byrde, R. J. W. (1979) "Role of Polysaccharide-Degrading Enzymes in Microbial Pathogenicity", Microbial Polysaccharides and Polysaccharases (Chapter 18):422-424.
(1991-92) "Technical Information", Sigma Plant Cell Culture 49-59.
Durzan Don J.
Ventimiglia Frank F.
Marx Irene
The Regents of the University of California
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