Targeted polymerized liposome contrast agents

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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424 121, 436829, A61K 9127

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active

055122949

ABSTRACT:
Polymerized liposome particles based upon lipids having a polymerizable functional group and a metal chelator to attach an imaging enhancement agent and lipids having an active targeting group to provide targeted polymerized liposome contrast agents. The polymerized imaging enhancement liposome particles interact with receptor targets holding the image enhancement agent to specific sites providing in vivo study by magnetic resonance, radioactive, x-ray or optical imaging of the expression of molecules in cells and tissues during disease and pathology.

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