Tachykinin antagonists

Details Tachykinin antagonists Tachykinin antagonists

1996-05-31

1998-06-02

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

514415, 514418, 514419, 548483, 548484, 548485, 548486, 548495, C07D20902, C07D20942, A61K 3140

Patent

active

057602484

ABSTRACT:
A description is given of tachykinin receptor antagonists having general formula (I) ##STR1## their preparation and use in pharmaceutical formulations.

REFERENCES:
patent: 5641802 (1997-06-01), Arcamone et al.
Hagiwara et al., J. Med. Chem., 36, 2266-2278 (1993).
Mantyh et al., Proc. Natl. Acad. Sci. USA, 85, 3235 (1988).
STN search report for: Potier et al., New NK-1 Tachykinin Receptor Antagonists Based on a Alicyclic Amino Acids as a Template: Stereoselective Synthesis and Chirality Investigation by NMR, Pept. 1994, Proc. Eur. Symp., 23rd, Meeting Date 1994, p. 315-, 1995.
Sisto et al., Synthesis and Biological Evaluation of Novel NK-1 Tachykinin Receptor Antagonists: The Use of Cycloalkyl Amino Acids as a Template, Biopolymers, vol. 36, No. 4, pp. 511-524, Oct. 1995.
Peters et al., Amer. Rev. Resp. Dis. 145,835 (1992).
Regoli et al., Pharmacology, 28, 301-320 (1984).
Hamel et al., Can. J. Pharm. Physiol., 66, 1361 (1988).

Affiliated with

Also associated with

Rating

Tachykinin antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tachykinin antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tachykinin antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1461622