Tachykinin antagonists

Details Tachykinin antagonists Tachykinin antagonists

1997-10-17

1999-01-05

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

N-c doai

514478, 514481, 514487, 514613, 514620, 514621, 514622, 514784, 560 29, 560 31, 560 37, 560 45, 560 47, 560 48, 560 56, 560100, 562445, A61K 3127, A61K 31165, C07C22936, C07C27120

Patent

active

058563547

ABSTRACT:
The invention concerns tachykinin antagonists. The compounds are neopeptides which have utility in treating disorders mediated by tachykinins. Such disorders are respiratory, inflammatory, gastrointestinal, ophthalmic, allergies, pain, vascular, diseases of the central nervous system, and migraine. Methods of preparing compounds and novel intermediates are also included. The compounds are expected to be especially useful in asthma and rheumatoid arthritis.

REFERENCES:
patent: 4727189 (1988-02-01), Hansen, Jr. et al.

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