T cell growth factor and method of making same

Details T cell growth factor and method of making same T cell growth factor and method of making same

1986-10-31

1989-04-18

Tarcza, John Edward

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

4351721, 4352402, 435948, 935101, 935109, C12P 2100, C12N 1500, C12N 500, C12R 191

Patent

active

048227358

ABSTRACT:
A mutant T-cell line of HSB-2-ERICR which produces a T cell Growth Factor is disclosed. The Mutant cells are sensitive to HAT Medium.

REFERENCES:
patent: 4473642 (1984-09-01), Gillis
Stadler et al, Journal of Immunology 127(5) pp. 1936-1940 (1981).
Okada et al, Proc. Natl. Acad. Sci. 78(12) pp. 7717-7721 (1981).
Irigoyen et al, Journal of Experimental Medicine 154 pp. 1827-1837 (1981).
Harwell et al, Journal of Experimental Medicine 152 (4) pp. 893-904 (1980).
Arnold et al, Journal of Immunological Methods 29 pp. 353-360 (1979).
Schrader et al, Journal of Immunology, 126(3) pp. 1101-1105 (1981).
Szybalski et al, Proc. Soc. Exp. Biol. Med. 101 pp. 662-666 (1959).
Littlefield, Science 145 pp. 709-710 (1964).

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