Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2005-07-19
2005-07-19
Chang, Ceila (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C560S155000
Reexamination Certificate
active
06919476
ABSTRACT:
A process for amino acid derivatives shown by the below general formula (I):(wherein R1means a hydrogen atom or a straight chain or branched chain alkyl group with 1-5 carbon atoms.) having an object to provide a process of the amino acid derivatives of the formula (I) and their synthetic intermediate, t-butoxycarbonylamino-ethylamine, whereby it requires no tedious procedure and is also good in yield, and its application to a mass production is easy, and to provide novel amino acid derivatives of the formula (IV), their synthetic intermediates, and a process thereof, characterized in that it comprises a step to obtain the amino acid derivatives shown by the general formula (I) by hydrolysis of compounds shown by the below formula (II):(wherein R1has the same meaning as described above, and R2means a straight chain or branched chain alkyl group with 1-4 carbon atoms.) as well as amino acid derivatives shown by the general formula (IV):(wherein R1means a hydrogen atom or a straight chain or branched chain alkyl group with 1-5 carbon atoms, and n means any one of integers 1-11.), and a process for the amino acid derivative, characterized in that it comprises a reduction step of benzyloxycarbonyl-ω-amino acid derivatives.
REFERENCES:
patent: 5595741 (1997-01-01), Huber et al.
patent: WO 97/30053 (1997-08-01), None
patent: WO 99/31121 (1999-06-01), None
patent: WO 2002020470 (2002-03-01), None
patent: WO 2002051797 (2002-07-01), None
Roeske et al, Journal of Organic Chemistry, vol. 41(7), (1976), pp1260-1261.
Roeske, Roger W., Selective Reduction of the Amide Carbonyl Group in Depeptides by Borane, J. Org. Chem. vol. 41, No. 7, 1976, pp 1260-1261.
Ikeda Hisafumi
Nakamura Yushin
Saito Isao
Chang Ceila
Credia Japan Co., Ltd.
Goldberg Richard M.
Reyes Hector M.
LandOfFree
T-butoxycarbonylaminoethylamine for the synthesis of PNA... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with T-butoxycarbonylaminoethylamine for the synthesis of PNA..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and T-butoxycarbonylaminoethylamine for the synthesis of PNA... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3378512