System for delivering an active substance for sustained release

Details System for delivering an active substance for sustained release System for delivering an active substance for sustained release

1991-12-31

1992-11-03

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Tablets, lozenges, or pills

424470, 424491, 424497, A61K 926, A61K 914

Patent

active

051607425

ABSTRACT:
A system for delivering an active substance has sustained release of the active substance in the intestinal tract. This delivery system is especially useful for an active substance such as a .beta.-lactam antibiotic which preferably has minimal exposure to the acidic environment of the stomach. Particles comprise an active ingredient disposed in a core which has at least one coating of a prolamine and one coating of an enteric compound thereon. The particles may be very small and suspended in a liquid medium.

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