Synthetic mammalian sulphamidase and genetic sequences encoding

Details Synthetic mammalian sulphamidase and genetic sequences encoding Synthetic mammalian sulphamidase and genetic sequences encoding

1995-04-19

1999-01-26

Lau, Kawai

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Hydrolase

4353201, 435325, 536 232, C12N 914, C12N 1563, C12N 510, C07H 2104

Patent

active

058637826

ABSTRACT:
The present invention relates generally to mammalian sulphamidase and to genetic sequences encoding same and to the use of these in the investigation, diagnosis and treatment of subjects suspected of or suffering from sulphamidase deficiency.

REFERENCES:
Mahuran, D. et al. (1983) "A rapid four column purification of 2-deoxy-D-glucoside-2-sulphamate sulphohydrolase from human liver" Biochim. Biophys. Acta 757:359-365.
Freeman, C. et al. (1986) "Human liver sulphamate sulphohydrolase" Biochem. J. 234:83-92, 1983.
Alberts, B. et al. Molecular Biology of the Cell, 2nd Ed., published 1989 by Garland Publ. (New York), pp. 258-266, 1989.
Coulter, P.M. II et al. (1983) "Identification of cortexin: a novel, neuron-specific, 82-residue membrane protein enriched in rodent cerebral cortex" J. Neurochem. 61:756-759.

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